Multibionta's effect on colds and flu
Effect of Lactobacillus gasseri PA 16/8, Bifidobacterium longum SP 07/3, B. bifidum MF 20/5 on common cold episodes: a double blind, randomized, controlled trial.
De Vrese M, et al. Clin Nutr. 2005 Aug;24(4):481-91
This clinical study investigated whether the consumption of a combination of three types of probiotics (Lactobacillus gasseri, Bifidobacterium longum and B. bifidum) for at least three months would influence the incidence, severity and duration of the common cold.
A randomized, double-blind, placebo-controlled intervention study with 479 healthy adults was performed during two winter/spring periods. The adults took daily vitamins and minerals either with (treated group) or without (control group) probiotic bacteria. Participants with colds recorded symptoms daily.
The duration of common cold episodes and days with fever during an episode were lower in the probiotic-treated group than in the control group. The study authors concluded that the intake of probiotic bacteria for at least three months significantly shortened common cold episodes by almost two days and reduced the severity of symptoms.
Effect of a dietary supplement containing probiotic bacteria plus vitamins and minerals on common cold infections and cellular immune parameters.
Winkler P et al. Int J Clin Pharmacol Ther. 2005 Jul;43(7):318-26.
This clinical study investigated whether using a dietary supplement containing probiotic bacteria plus vitamins and minerals for three months in winter/spring could affect the duration, frequency and severity of the common cold.
A randomized, double-blind, placebo-controlled intervention study was conducted on 477 healthy adults who were randomly assigned to receive either a daily probiotic multivitamin or a placebo for three or for five-and-a-half months.
The subjects recorded common cold and influenza-like symptoms daily. The researchers found a relative reduction of 19% in the total symptom score (p = 0.12), 25% in influenza symptoms (p = 0.09), and 54% in the number of days with fever (p = 0.03). The duration of these infections was not affected. The researchers concluded that the intake of a probiotic multivitamin during a period of at least three months in winter/spring may reduce the incidence and the severity of symptoms of common colds.